|
Symbol Name ID |
Bcl2l1
BCL2-like 1 MGI:88139 |
| * | Aspects of the system are reported to show a normal phenotype. |
| Darker colors indicate more annotations |
| Human Phenotypes | Leukocytosis |
Abnormal granulocyte morphology |
Abnormal basophil morphology |
Acute lymphoblastic leukemia |
Ph-positive acute lymphoblastic leukemia |
T-cell acute lymphoblastic leukemias |
Chronic myelogenous leukemia |
Myeloproliferative disorder |
Lymphadenopathy |
Splenomegaly |
Hepatosplenomegaly |
Peritoneal abscess |
| Disease(s) Associated with BCL2L1 | ||||||||||||
| acute lymphoblastic leukemia | ||||||||||||
| chronic myeloid leukemia | ||||||||||||
| pancreatic cancer |
| Mouse Phenotypes | immune system phenotype |
decreased T cell proliferation |
increased T cell proliferation |
decreased thymocyte number |
decreased double-positive T cell number |
decreased memory T cell number |
increased memory T cell number |
decreased IgG1 level |
abnormal T cell physiology |
abnormal memory T cell physiology |
decreased interleukin-2 secretion |
increased interleukin-2 secretion |
decreased susceptibility to experimental autoimmune encephalomyelitis |
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| Availability | Mouse Genotype | |||||||||||||
| Bcl2l1tm1Cant/Bcl2l1tm1Cant | ||||||||||||||
| Tg(Lck-Bcl2l1)1Cant/? | ||||||||||||||
| Bcl2l1tm1Ywh/Bcl2l1tm1Ywh Tg(Lck-cre)548Jxm/? (conditional) |
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| Bcl2l1tm1Dlo/Bcl2l1tm1.1Mam Tg(Aicda-cre)9Mbu/0 (conditional) |
* | |||||||||||||
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/23/2024 MGI 6.23 |
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